Everything You Need for Your RNA-Related Workflows

We’ve told you before that we offer a broad portfolio of reagents for purification, quantitation, detection, synthesis and manipulation of RNA. But did you know that these products are available from bench-scale to commercial-scale to enable both academic and industrial needs? Further, we provide these products at quality levels that support vaccine and diagnostic manufacturing. Experience improved performance and increased yields, enabled by our expertise in enzymology.

Select an application to learn more:

 

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RNA Purification:

Transform your RNA purification experience with Monarch®

Quickly and easily extract up to 100 μg of high-quality total RNA from multiple sample types – all with one convenient kit!

• Use with blood, cells, tissues, tough-to-lyse samples, saliva and swabs
• Validated for viral RNA extraction from clinically-relevant samples (automatable on the QIAcube® and KingFisher® Flex)
• Effectively purify total RNA of all sizes, including small RNA (<200 nt)

Learn more and request a sample

Quickly and easily clean up and concentrate RNA after extraction or following a variety of enzymatic reactions, including DNase I treatment, in vitro transcription, and end-modifications.

• Obtain highly-pure RNA in minutes with no carryover contamination
• Available in 3 different binding capacities: 10 μg, 50 μg and 5 00 μg
• Elute in low volumes for highly concentrated RNA (T2030: ≥ 6 μl, T2040: ≥ 20 μl and T2050: ≥ 50 μl)
• Also adaptable for extraction of total RNA from cells, saliva and swabs

Learn more

 

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RNA-seq:

Get even more from less with NEBNext® Ultra™ II Library Prep for RNA-seq

Generate high-quality libraries even with limited amounts of RNA

• Save time with streamlined workflows, reduced hands-on time and automation compatibility
• Order reagents specific to your needs, including directional and non-directional kits, rRNA depletion and poly(A) mRNA isolation
• Adaptors and primers (12- and 96-index) available separately
• Working with small RNA? Minimize adaptor-dimer formation while achieving high yield, diverse multiplex libraries with our unique
  small RNA library preparation workflow.

View performance data and request a free sample

 

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RNA Detection:

Optimize your RT-qPCR with Luna®

Experience superior performance across a wide variety of sample types

• Luna WarmStart® RT paired with Hot Start Taq. Unique aptamer technology increases reaction specificity and robustness
• Compatible with automation and reaction miniaturization
• High concentration 4X mix is ideal for viral targets
• Luna SARS-CoV-2 RT-qPCR Multiplex Assay Kit provides accurate and sensitive detection of SARS-CoV-2
• Non-interfering visible tracking dye helps to eliminate pipetting errors

Try a sample and see how Luna outperforms the competition

 

Products and support for LAMP/RT-LAMP workflows

Experience superior performance across a wide variety of sample types

• Simple, one-step solutions for Loop-Mediated Isothermal Amplification (LAMP) of DNA or RNA (RT-LAMP) targets
• Multiple polymerase options with strand displacement activity
• NEB LAMP Primer Design Tool for optimal LAMP primers

Learn more about how NEB supports isothermal amplification

 

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RNA Synthesis:

Synthesize high-quality RNA with reagents designed to simplify your workflow 

• Generate high yields of high quality mRNA with our HiScribe^™ in vitro transcription kits, including our new HiScribe^™ T7 mRNA Kit with CleanCap^® Reagent AG
• Try our Vaccinia Capping System for efficient enzymatic capping of mRNA
• Synthesize mRNA for therapeutics and vaccines using our GMP-grade* IVT reagent portfolio
• Rapidly synthesize guide RNAs for CRISPR/Cas9 experiments with our EnGen® sgRNA Synthesis Kit, S. pyogenes

  

 

"GMP-grade" is a branding term NEB uses to describe reagents manufactured at NEB’s Rowley facility. The Rowley facility was designed to manufacture reagents under more rigorous infrastructure and process controls to achieve more stringent product specifications and customer requirements. Reagents manufactured at NEB’s Rowley facility are manufactured in compliance with ISO 9001 and ISO 13485 quality management system standards. However, at this time, NEB does not manufacture or sell products known as Active Pharmaceutical Ingredients (APIs), nor does NEB manufacture its products in compliance with all of the Current Good Manufacturing Practice regulations.

One or more of these products are covered by patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. For more information, please email us at busdev@neb.com. The use of these products may require you to obtain additional third party intellectual property rights for certain applications.